b' This is an incredibleCell and Gene Therapy opportunity to help patients facing serious health issuesGrowth in Coloradoand will change the face of medicine as we know it. 30+ Companies in State 1,100+ Current EmployeesTERRY FRY, M.D.EXECUTIVE DIRECTORPLAY VIDEO PLAYGATES INSTITUTE Stages of Technology1,000 New Jobs Development Created in 5 YearsContinuing the Growth on Campus balance of research, development, and implementation that canRESEARCH & DEVELOPMENT/21Fitzsimons Innovation Community completed constructionserve as a model for other hubs.PRECLINICAL RESEARCH: on Bioscience 5, a state-of-the-art, flexible bioscience centerHaving all those together and all those people talking to each$230M Being Raised in that further delivers on the Communitys vision to advanceother and putting their heads together is really critical, SmithCLINICAL RESEARCH 21(PHASE 1-3):Current Funding Roundshealth and care. The 90,000-square-foot facility is the firstsaid. I think if one of those pieces is missing, youre probably building in the Fitzsimons Innovation Community with full- not going to be able to effectively and efficiently move theMANUFACTURING/14scale manufacturing for cell and gene therapy. Bioscienceneedle forward.COMMERCIALIZATION/ POST-MARKET: 5 is designed to support its member companies overallIn addition to his role at the Blood Disorder and Cell Therapies development and optimize the scientific advancements Center, Smith serves as the Medical Director for UCHealth andSource: Colorado BioScience Association. CBSA data representswithin the Community ecosystem.the CU Innovation Centers, overseeing collaborations betweenprojections at the low end of each range for jobs and fundraising.Fitzsimons Innovation Community is growing with companiesresearch and private companies. He thinks this part of his from an incubator with small startups (Bioscience 1) to growth-job is another important bridge to take crucial research from and later-stage companies (Bioscience 2 and Bioscience 3), academia to commercialization. and the ability for commercial companies to continue scaling The academic world must partner closely if we are to make life in Bioscience 5 with cell and gene therapy manufacturing tobetter for our patients, he said. Its not sufficient for me to be ableAdvancing Cell Therapy take significant products to market. to cure cancer in a mouse, we have to be able to take that to the All of this combined has created a thriving ecosystem for cellnext level, and you cannot do that without a commercial partner.and gene therapy that is crucial to its innovative future with aThrough Clinical TrialsBIOSCIENCE 5 FITZSIMONS INNOVATION COMMUNITY Active cell therapy trials throughCutting-edge pediatric cell the UCHealth Blood Disorders therapy trials at the Childrens and Cell Therapies Center Hospital Colorado Center for University of ColoradoCancer and Blood Disorders:Anschutz Medical Campus:ACTIVE TRIALS: 16 TRIALS: 9COMPANIES IN TRIALS: 9 GROUPS/COMPANIES 9IN TRIALS:TUMOR TYPES:6Source: CU Innovations and University of Colorado Anschutz Medical Campus14Fitzsimons Innovation Community Annual Innovation Report 15'